Russetid på Kolbotn :)

Russetid på Kolbotn :)

Oslo, Norge

Weather Underground PWS IOSLOOSL24

Monday, January 28, 2008

Possible Future Malaria Vaccine

It may be too late for the millions, or perhaps even billions of people throughout history who have been infected with Malaria. However, it looks like there might be some hope for the future generations in a research project being held in Tanzania, where Malaria is the nations #1 killer and my lovely wife is practicing Physical Therepy at a medical facility in Moshi, Kilimanjaro province.

I have Google News customized into different categories. You might guess that I have the election, the UPF, the Unification Church, and others as extra categories. Among these extra news search categories I've added I also have Tanzania so I can keep track of the goings on in the country which currently engulfs my girl. That's how I ended up finding the fallowing article on from The East African.

Malaria vaccine undergoes clinical trials in Tanzania

The EastAfrican

Researchers at the National Institute for Medical Research (NIMR) in Tanga Region are carrying out a clinical trial to evaluate the safety and immunological potential of a candidate malaria vaccine called MSP3-LSP.

Speaking to The EastAfrican in Dar es Salaam last week, the principal researcher for the trial, Dr John Lusingu, said the launch of the new vaccine would take place in Korogwe District.

The term MSP3-LSP stands for merozoite surface protein 3-long synthetic peptide. Similar tests were conducted successfully for healthy adults in Switzerland and Burkina Faso.

Dr Lusinga added that the two different dosages (15 and 30 microgrammes) of MSP3 are now being tested in a staggered process among child populations to further demonstrate its safety and any immediate or delayed adverse effects.

The trial is being run by a team of NIMR-Tanga researchers at the Kwashemshi Vaccination Centre in Korogwe district, said Dr Lusinga.

The study, which was approved by the Tanzania National Health Research Ethics Review Committee and the Tanzania Food and Drugs Authority, involves 45 healthy, randomly selected children aged one to two years.

Dr Lusinga said the researcher has divided children into two groups comprising 23 and 22 children respectively. In the first group, 15 children are receiving a lower dose (15 microgrammes) of the test vaccine MSP3, while the remaining eight (control group) are receiving Hepatitis B vaccine.

According to Dr Lusingu, in the second group, 15 children are receiving a higher dose (30 microgrammes) of MSP3 and the remaining 7 (control group) are also receiving a Hepatitis B vaccine.

Immunisations in the two groups are staggered. In the second group, they are administered two weeks later after a thorough safety evaluation of the outcome of vaccination with the lower dose.

Each child will receive a total of three immunisations.

“Malaria accounts for 80 per cent of deaths among children below five in Tanzania.

We are very proud to be part of a process aimed at finding lasting solutions against Tanzania’s biggest killer,” Dr Lusinga said.

Dr Lusingu has assured the public that children will be closely monitored during the entire study period of 13 months.

The African Malaria Network Trust (Amanet) is sponsoring the study. In September last year, the Dar es Salaam based non-governmental organisation donated $50,000 to the National Institute for Medical Research for a project that will run for three years.

The Health Research Ethics (HRE) project, which the money will fund, aims at strengthening ethical practices in health research in Tanzania.

The project will also involve activities aimed at improving the ethical review committees at NIMR centres and stations.

According to Amanet managing trustee, Prof Wen Kilama, the HRE project will also enable the committees to conduct meetings regularly and review proposals using agreed standard operating procedures.

“Through this streamlining and empowerment of institutional research ethics committees, NIMR will be addressing the overall problem of a rising workload of proposals waiting to be reviewed, and at the same time ensure that the safety and wellbeing of human health research participants are protected,” said Prof Kilama.

Prof Kilama added that, besides funding for this trial, Amanet has contributed extensively in capacity strengthening, trial site development and training at NIMR-Tanga.

The mechanisms mediating protection in humans were analysed by clinical experiments of passive protection in patients, and the main mechanism, which was employed to screen the ca. 5300 proteins of the malaria parasite (Plasmodium falciparum), identified MSP3 as the main target.

Click here for an informative PDF of the subject of malaria vaccines.

Click here for a more detailed article on this particular study.

This is Fipher posting from Vineyard Haven, MA, & hoping for you the keep healthy.

Tuesday, January 22, 2008

NAACP President: Ron Paul Is Not A Racist

Austin NAACP President Nelson Linder, who has known Ron Paul for 20 years, unequivocally dismissed charges that the Congressman was a racist in light of recent smear attempts, and said the reason for him being attacked was that he was a threat to the establishment.

I truly hope that this can be spread around so this rumor of Dr. Paul being a racists can be fully squashed. I don't agree with him 100% on all the issues, but I cannot imagine anyone who believes so strongly in individual liberty could possibly be at all racist. Racism and Libertarianism are completely counter to won another. If you read up on Libertarianism, I'm sure you will agree.

Click here for an article by Ron Paul about racism and the government's role in it.

"Yet it is the Federal government more than anything else that divides us along race, class, religion, and gender lines.  The Federal government, through its taxes, restrictive regulations, corporate subsidies, racial set-asides, and welfare programs, plays far too large a role in determining who succeeds and who fails in our society." - Rep. Ron Paul, MD, December 24th, 2002